Prevent Colon Cancer with a Colonoscopy Starting at Age 45. South Central Gastroenterology Offers Direct Access Colonoscopy. It used to be 50. Now, anyone approaching their 45th birthday should talk to their primary care provider to schedule a possibly lifesaving colonoscopy. A colonoscopy is an exam that can stop colorectal cancer, which is among the most … Continue reading 45 is the New 50 When it Comes to Colonoscopies | SC Gastroenterology